Structure Activity Studies on Chemically Modified Homologues of the Antibiotic Phytotoxic Leucinostatin A.
نویسندگان
چکیده
منابع مشابه
Structure activity studies on chemically modified homologues of the antibiotic phytotoxic leucinostatin A.
The synthesis and a conformational study of a number of homologues of the well known antibiotic, phytotoxic leucinostatin A are reported. The circular dichroism of all the compounds are discussed. Some conclusions on the SAR of these compounds are drawn. The influence of the alpha-helical conformation and/or the increased lipophile character on their interesting biological activities is emphasi...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1995
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.48.254